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Coffee consumption is associated with a reduced risk of colorectal cancer recurrence and all-cause mortality

February 12, 2024
Oyelere AM, Kok DE, Bos D, Gunter MJ, Ferrari P, Keski-Rahkonen P, de Wilt JHW, van Halteren HK, Kouwenhoven EA, van Duijnhoven FJB, Kampman E

Conclusion Statement

In conclusion, our results suggest that coffee consumption may be associated with a lower risk of CRC recurrence in patients with stages I–III CRC. We also observed a nonlinear, U-shaped association between coffee consumption and all-cause mortality with the lowest risk observed for the intake of 3–5 cups/d of coffee. Although we cannot infer a cause-and-effect relationship in our observational study, our findings could inform future intervention studies and provide evidence to develop guidelines for CRC patients. More studies are needed to fully understand the mechanisms by which coffee might improve CRC prognosis.

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Citations

Oyelere AM, Kok DE, Bos D, Gunter MJ, Ferrari P, Keski-Rahkonen P, de Wilt JHW, van Halteren HK, Kouwenhoven EA, van Duijnhoven FJB, Kampman E. Coffee consumption is associated with a reduced risk of colorectal cancer recurrence and all-cause mortality. Int J Cancer. 2024 Jun 15;154(12):2054-2063. doi: 10.1002/ijc.34879. Epub 2024 Feb 12. PMID: 38346920.

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