Coffee Consumption May Mitigate the Risk for Acute Kidney Injury: Results From the Atherosclerosis Risk in Communities Study

In ARIC, higher amounts of average daily coffee consumption were associated with a lower risk of incident AKI. Coffee consumption was highest in males, White participants, smokers, individuals without diabetes, and people with lean BMIes, normal BP, and higher total energy intake per day. When we adjusted for age, sex, race-center, education, total energy intake, physical activity, smoking, alcohol intake, diet, BP, diabetes status, use of antihypertensive medication, kidney function, and BMI, individuals who consumed any amount of daily coffee still had an 11% lower risk of developing AKI compared with individuals who had never consumed coffee. AKI risk reduction was dose-dependent, with the most substantial reductions observed in the group that consumed 2 to 3 cups/d of coffee.